Clinicopathological Profile and Locoregional Control in Malignant Salivary Gland Tumours

Abstract

Introduction: Salivary gland tumours (SGT) are relatively less common and they exhibit a wide variety of morphological and histological diversity. Thus, diagnosis and management of salivary gland tumours are still complex and challenging. The objective of this study is to evaluate the clinicopathologic characteristics, treatment outcomes of malignant SGTs. Materials and Methods: Retrospective analysis of all Malignant SGTs presented to our institute from 2017 to 2021 was done. The clinical data, histopathological features and treatment outcome were statistically analyzed. Results: A total of 60 patients were included in the study with a mean age of 52.8years and overall male preponderance. All the patients were treated with curative Surgery. Adjuvant radiotherapy was given in the patients with high-risk features.70% of the malignant SGTs in this study had parotid gland involvement and 24% in submandibular gland. Mucoepidermoid carcinoma (53%)  was the most common histopathological variant. With the median follow-up of 28 months, the prevalence of recurrence was 15% (n=9). Conclusions: The Clinicopathological profile of SGTs in our study were in agreement with those studies reported from India and other parts of the world. Tumour stage, grade and adjuvant therapy have a significant relationship with the local control and Relapse free survival in malignant SGTs.