A Clinicopathological Study of Soft Tissue Tumors in Tertiary care institute in Uttar Pradesh

Abstract

Background:
Soft tissue tumors are a heterogeneous group of neoplasms that can occur at any age and in various anatomical locations. They range from benign to malignant types. While some are more common in children, others primarily affect the elderly. Recognizing their histomorphological patterns is crucial for accurate diagnosis and effective management. Aim: This study is aimed to evaluate the histomorphological characteristics of soft tissue tumors with respect to age, gender, and type distribution. Materials and Methods: A combined retrospective and prospective observational study was conducted over one year in the Department of Pathology at GSVM Medical college, Kanpur. A total of 252 cases were analyzed. Data were collected from departmental archives and samples were obtained from the Department of General Surgery along with clinical requisition forms detailing demographic and clinical information. Results: Among the 252 cases studied, patient ages ranged up to 95 years. The highest incidence was in the 31–40 years age group (74 cases, 29.37%), followed by the 21–30 years group (63 cases, 25.0%). The cohort included 84 males (33.3%) and 168 females (66.7%). Of the 252 cases evaluated for tumor type, 228 (91.93%) were benign, and 20 (8.06%) were malignant. Lipomas were the most frequent benign tumors (75 cases, 29.7%), followed closely by leiomyomas (68 cases, 26.9%). Dermatofibrosarcoma protuberans was the most common intermediate tumors (6 cases, 2.3%). Alveolar rhabdomyosarcoma was the most common malignant tumour ( 5cases, 1.98%) followed by malignant spindle cell tumour (3 cases, 1.19%). Conclusion: Soft tissue tumors were more prevalent in females, particularly in the third and fourth decades of life. Benign tumors, especially lipomas and leiomyomas, predominated over malignant types. The study highlights the relevance of demographic factors in the diagnosis and epidemiology of soft tissue tumors.