Incidence of Microalbuminuria in Newly Diagnosed Patients of Type II Diabetes Mellitus: - A Cross-Sectional Study

Abstract

Background: Diabetes mellitus and hypertension are the two most important lifestyle diseases in India, closely related to chronic kidney disease. India is the “Diabetes Capital” of the world, according to ICMR’s largest survey on diabetes and other metabolic diseases in India conducted between October 18, 2008, to December 17, 2020.

Aims and objectives: To find the incidence of Microalbuminuria, at the time of diagnosis or within one week of diagnosis of Diabetes Mellitus Type-II, to find the overall incidence of Microalbuminuria at the time of diagnosis of Diabetes Mellitus correlation of glycosylated haemoglobin, an indicator of glycaemic status, and the incidence of Microalbuminuria.

Results: Among the 150 subjects, microalbuminuria was found in 16 (10.7%) subjects.

Materials and methods: Mann–Whitney Test was used to compare the Glycaemic Parameters based on the Incidence of Microalbuminuria among study subjects. Receiver operating characteristic curve (ROC) analysis was performed to predict the Microalbuminuria using Glycaemic Parameters among study subjects. The level of significance was set at p < 0.05.

Conclusion: The difference is statistically significant at p < 0.001. It was found that the predictive value of HbA1c for a cutoff set at > 8.1% has the best chance of correctly predicting microalbuminuria with a sensitivity of 93.8 and specificity of 92.2 (95% Confidence Interval) at a p-value of < 0.001 which is highly significant statistically.