Clinicopathological Spectrum of all Non-Hematological Paediatric Tumours

Abstract

Introduction: Paediatric tumours, though rare, are a leading cause of cancer-related deaths in children. Thus, we aimed to study the clinic-pathological spectrum of all non-haematological paediatric tumours.

Methodology: In this retrospective and prospective investigation, we incorporated confirmed histological cases of non-haematological paediatric tumours in individuals aged 0-18 years spanning from 2019 to 2022.

Results: The majority of cases in 2019 and 2020 were between 15-18 years, while in 2021, the majority were in the 10–14-year age group. Males constituted a higher percentage across all years. Leukaemia was the most common malignancy in all three years, with notable variations in other tumour types. Benign tumours were more prevalent in 2019 and 2021, while malignant tumours were more common in 2020. Hematological malignancies were more frequent across all years, with acute lymphocytic leukaemia being the most prevalent. Significant age (15-18 years mostly) and tumour-type variations were observed among the children over the three years.

Conclusion: While this hospital-based study cannot offer precise incidence rates, it provides valuable insights into paediatric tumour trends and patterns. Unlike previous studies that predominantly concentrated on paediatric malignant tumours, our analysis encompasses benign and malignant tumour cases.